HCID 21253084, 화합물 → HCID 21253068, 화합물

HRID 1530851노트

반응식

HRID 1530851 반응식
[ClH:1].[Br:2][C:3]1[CH:12]=[C:11]([N+:13]([O-])=O)[C:10]([NH2:16])=[C:9]2[C:4]=1[CH2:5][CH2:6][NH:7][CH2:8]2>CO.[Pd]>[ClH:1].[BrH:2].[CH2:8]1[C:9]2[C:4](=[CH:3][CH:12]=[C:11]([NH2:13])[C:10]=2[NH2:16])[CH2:5][CH2:6][NH:7]1

참가 물질

4

반응물 1

HCID 21253084HCID 21253084, 화합물

생성물 1

HCID 21253068HCID 21253068, 화합물수율 99%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

The product from Example 5 (7 g) in 250 mL of methanol was treated with 20% Pd/C (1 g) and shaken on a Parr apparatus under a hydrogen atmosphere (50 psi) for 16 h at ambient temperature. The catalyst was removed by filtration and the filtrate evaporated to give the product as a purple solid (6.3 g, 99% yield) that was used immediately without further purification.

후처리

  1. customThe catalyst was removed by filtration
  2. customthe filtrate evaporated

출처 및 근거

ORD 기록
ord-3ecbf170590c47aab876e1418107ae61
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06197771B1

반응 노트

불러오는 중…