3,4-dihydro-2H-pyrano[2,3-c]pyridine-6-carbaldehyde → 3-Chloro-4-({(3r,4s)-4-[(3,4-dihydro-2h-pyrano[2,3-c]pyridin-6-ylmethyl)amino]-3-hydroxy-1-piperidinyl}methyl)-4,5-dihydro-7h-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one hydrochloride

반응식

[NH2:1][C@H:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH:9]2[C:13]3=[C:14]([Cl:22])[CH:15]=[N:16][C:17]4[CH:18]=[CH:19][C:20](=[O:21])[N:11]([C:12]=43)[CH2:10]2)[CH2:4][C@H:3]1[OH:23].[O:24]1[C:29]2=[CH:30][N:31]=[C:32]([CH:34]=O)[CH:33]=[C:28]2[CH2:27][CH2:26][CH2:25]1>ClCCl.CO>[ClH:22].[Cl:22][C:14]1[CH:15]=[N:16][C:17]2[CH:18]=[CH:19][C:20](=[O:21])[N:11]3[CH2:10][CH:9]([CH2:8][N:5]4[CH2:6][CH2:7][C@H:2]([NH:1][CH2:34][C:32]5[CH:33]=[C:28]6[CH2:27][CH2:26][CH2:25][O:24][C:29]6=[CH:30][N:31]=5)[C@H:3]([OH:23])[CH2:4]4)[C:13]=1[C:12]=23