N1,N1-Dimethyl-N3-(2-nitrophenyl)-1,3-propanediamine → N~1~-[3-(Dimethylamino)propyl]benzene-1,2-diamine

HRID 1532639노트

반응식

HRID 1532639 반응식
[CH3:1][N:2]([CH3:16])[CH2:3][CH2:4][CH2:5][NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-])=O>C(O)C.[C].[Pd]>[CH3:16][N:2]([CH3:1])[CH2:3][CH2:4][CH2:5][NH:6][C:7]1[C:8]([NH2:13])=[CH:9][CH:10]=[CH:11][CH:12]=1

참가 물질

4

반응물 1

HCID 210504N1,N1-Dimethyl-N3-(2-nitrophenyl)-1,3-propanediamine

생성물 1

HCID 14174121N~1~-[3-(Dimethylamino)propyl]benzene-1,2-diamine수율 100.1%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

10% of palladium-carbon (0.18 g) was added to a solution containing N1,N1-dimethyl-N3-(2-nitrophenyl)-1,3-propanediamine (0.90 g) in ethanol (9 ml) and stirred for 2.5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (0.78 g) as reddish brown oil.

후처리

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-78640b95da544b988deb1b71a3fca6fa
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

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