HCID 15518370, 화합물 → HCID 22013785, 화합물

HRID 1532646노트

반응식

HRID 1532646 반응식
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:39])[CH3:38])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

참가 물질

4

반응물 2

HCID 15518370HCID 15518370, 화합물HCID 21866389Hydrogen chloride-ethyl acetate

생성물 1

HCID 22013785HCID 22013785, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

4N Hydrochloric acid/ethyl acetate solution (0.11 ml) was added to a solution containing 3-(2-henicosyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.20 g) in ethyl acetate (2 ml). After being stirred for 20 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.19 g) as white solid.

후처리

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethanol-ethyl acetate

출처 및 근거

ORD 기록
ord-91669861cc894b55a7fdec9684bdd122
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

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