N,N-Dimethyl-1,3-propanediamine → HCID 22013769, 화합물

HRID 1532657노트

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HRID 1532657 반응식
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH2:6].Cl[C:9]1[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][C:10]=1[N+:20]([O-:22])=[O:21]>C(OCC)(=O)C>[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][NH:6][C:9]1[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][C:10]=1[N+:20]([O-:22])=[O:21]

참가 물질

4

반응물 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 1268247Ethyl 4-chloro-3-nitrobenzoate

생성물 1

HCID 22013769HCID 22013769, 화합물수율 101.2%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

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온도
125 °C

실험 절차

N,N-Dimethy-1,3-propanediamine (1.41 g) was added to ethyl 4-chloro-3-nitrobenzoate (1.59 g) and stirred for 12 hours at 125° C. The reaction mixture, with ethyl acetate added thereto, was washed with 1N sodium hydroxide aqueous solution, water, and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (2.07 g) as brown oil.

후처리

  1. washwas washed with 1N sodium hydroxide aqueous solution, water, and saturated brine successively
  2. dry with materialdried over sodium sulfate anhydride
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-1f6d9195e4494539b03d21d4b032ff02
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

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