HCID 22013769, 화합물 → Ethyl 3-amino-4-[[3-(dimethylamino)propyl]amino]benzoate

HRID 1532658노트

반응식

HRID 1532658 반응식
[CH3:1][N:2]([CH3:21])[CH2:3][CH2:4][CH2:5][NH:6][C:7]1[CH:17]=[CH:16][C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:9][C:8]=1[N+:18]([O-])=O>C(O)C.[C].[Pd]>[NH2:18][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][C:7]=1[NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:21])[CH3:1])[C:11]([O:13][CH2:14][CH3:15])=[O:12]

참가 물질

4

반응물 1

HCID 22013769HCID 22013769, 화합물

생성물 1

HCID 22013774Ethyl 3-amino-4-[[3-(dimethylamino)propyl]amino]benzoate수율 101.9%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

10% of palladium-carbon (0.40 g) was added to a solution containing ethyl 4-{[3-(dimethylamino)propyl]amino}-3-nitrobenzoate (2.02 g) in ethanol (20 ml) and stirred for 5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (1.85 g) as dark red oil.

후처리

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-cedc4bdd46bf4da08a0a95c3a88e3aad
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

반응 노트

불러오는 중…