N,N-Dimethylethylenediamine → HCID 22013736, 화합물

HRID 1532689노트

반응식

HRID 1532689 반응식
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].Cl[C:8]1[CH:17]=[CH:16][C:11]([C:12]([NH:14][CH3:15])=[O:13])=[CH:10][C:9]=1[N+:18]([O-:20])=[O:19]>C(OCC)(=O)C>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH:5][C:8]1[CH:17]=[CH:16][C:11]([C:12]([NH:14][CH3:15])=[O:13])=[CH:10][C:9]=1[N+:18]([O-:20])=[O:19]

참가 물질

4

반응물 2

HCID 66053N,N-DimethylethylenediamineHCID 7992864-chloro-N-methyl-3-nitrobenzamide

생성물 1

HCID 22013736HCID 22013736, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
100 °C

실험 절차

N,N-Dimethylethylenediamine (3.30 ml) was added to 4-chloro-N-methyl-3-nitrobenzamide (3.220 g) and the mixture was stirred for 14 hours at 100° C. The reaction mixture, with ethyl acetate added thereto, was washed with 1N sodium hydroxide aqueous solution and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (3.687 g) as yellowish orange solid.

후처리

  1. washwas washed with 1N sodium hydroxide aqueous solution and saturated brine successively
  2. dry with materialdried over sodium sulfate anhydride
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-654257d6142042fdb74bfa23f2db7568
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

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