HCID 22013773, 화합물 → HCID 22013746, 화합물

HRID 1532695노트

반응식

HRID 1532695 반응식
[CH3:1][N:2]([CH3:20])[CH2:3][CH2:4][NH:5][C:6]1[CH:16]=[CH:15][C:9]([C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[CH:8][C:7]=1[N+:17]([O-])=O>C(O)C.[C].[Pd]>[NH2:17][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][C:6]=1[NH:5][CH2:4][CH2:3][N:2]([CH3:20])[CH3:1])[C:10]([N:12]([CH3:14])[CH3:13])=[O:11]

참가 물질

4

반응물 1

HCID 22013773HCID 22013773, 화합물

생성물 1

HCID 22013746HCID 22013746, 화합물수율 103.3%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

10% of palladium-carbon (0.535 g) was added to a solution containing 4-{[2-(dimethylamino)ethyl]amino}-N,N-dimethyl-3-nitrobenzamide (2.672 g) in ethanol (27 ml) and the mixture was stirred for 5.5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (2.464 g) as blackish brown oil.

후처리

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-89184bdc515949dbb33433a613935788
출처 데이터셋
uspto-grants-2001_03
특허 번호
US06204264B1

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