Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
[1,3]Oxathiolo[5,4-c]pyridine-6-carbaldehyde → 4-({4-[([1,3]oxathiolo[5,4-c]pyridin-6-ylmethyl)amino]-1-piperidinyl}methyl)-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | [1,3]Oxathiolo[5,4-c]pyridine-6-carbaldehyde | HCID 59254367 | — |
| 반응물 | 4-[(4-Amino-1-piperidinyl)methyl]-4,5-dihydro-7h-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one dihydrochloride salt | HCID 68685371 | — |
| 생성물 | 4-({4-[([1,3]oxathiolo[5,4-c]pyridin-6-ylmethyl)amino]-1-piperidinyl}methyl)-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one hydrochloride | HCID 68688399 | — |
반응 단계
The free base of the title compound was synthesised from 4-[(4-amino-1-piperidinyl)methyl]-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one dihydrochloride salt and [1,3]oxathiolo[5,4-c]pyridine-6-carbaldehyde (for a synthesis see WO2004058144, Example 61) according to the general method of Example 2(h).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732461B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-4a0006bc761c4184b305e3d17ebbb089 |
| 출처 메모 | uspto-grants-2010_06 |