4-Hydroxy-4-(6-methoxypyridin-3-YL)cyclohexanone → N-{1-[4-Hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-2-[1-methyl-5-(1,2,2,2-tetrafluoro-1-methoxy-ethyl)-1H-indazol-3-ylamino]-acetamide

반응식

[NH:1]1[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH3:26])[c:12]3[cH:13][cH:14][c:15]([C:18]([C:19]([F:20])([F:21])[F:22])([O:23][CH3:24])[F:25])[cH:16][c:17]23)=[O:27])[CH2:4]1.[OH:28][C:29]1([c:36]2[cH:37][n:38][c:39]([O:42][CH3:43])[cH:40][cH:41]2)[CH2:30][CH2:31][C:32](=[O:35])[CH2:33][CH2:34]1>>[N:1]1([CH:32]2[CH2:31][CH2:30][C:29]([OH:28])([c:36]3[cH:37][n:38][c:39]([O:42][CH3:43])[cH:40][cH:41]3)[CH2:34][CH2:33]2)[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH3:26])[c:12]3[cH:13][cH:14][c:15]([C:18]([C:19]([F:20])([F:21])[F:22])([O:23][CH3:24])[F:25])[cH:16][c:17]23)=[O:27])[CH2:4]1

참가 물질

반응물 2

HCID 529879954-Hydroxy-4-(6-methoxypyridin-3-YL)cyclohexanone

HCID 67478704HCID 67478704, 화합물

생성물 1

HCID 67478901N-{1-[4-Hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-2-[1-methyl-5-(1,2,2,2-tetrafluoro-1-methoxy-ethyl)-1H-indazol-3-ylamino]-acetamide

출처 및 근거

ORD 기록: ord-5b4bd84f6ca749f299001168cd577e62
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…