2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 2-{[5-(Acetylamino)-6-methylpyridin-2-yl]amino}-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

반응식

[Cl:22][c:23]1[cH:24][cH:25][c:26]([NH:30][C:31]([CH3:32])=[O:33])[c:27]([CH3:29])[n:28]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:23]1[cH:24][cH:25][c:26]([NH:30][C:31]([CH3:32])=[O:33])[c:27]([CH3:29])[n:28]1

참가 물질

반응물 2

HCID 595256192-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

HCID 59525698N-(6-chloro-2-methylpyridin-3-yl)acetamide

생성물 1

HCID 595257512-{[5-(Acetylamino)-6-methylpyridin-2-yl]amino}-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

출처 및 근거

ORD 기록: ord-2cb781d33453480a8f7c7edeb249f9ae
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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