3-Chlorobenzoic Acid → Loratadine N-oxide

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[CH2:7][CH2:8][c:9]1[c:10]([n:11][cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:20][CH2:21]1.[Cl:38][CH2:39][Cl:40].[OH:28][C:29]([c:30]1[cH:31][c:32]([Cl:33])[cH:34][cH:35][cH:36]1)=[O:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:27]1)[CH2:7][CH2:8][c:9]1[c:10]([n+:11]([O-:28])[cH:12][cH:13][cH:14]1)[C:15]2=[C:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:20][CH2:21]1

참가 물질

반응물 3

HCID 4473-Chlorobenzoic Acid

HCID 3957Loratadine

HCID 6344Dichloromethane

생성물 1

HCID 29982763Loratadine N-oxide

출처 및 근거

ORD 기록: ord-3e6552a0bf87444c9f1c09073fee1b95
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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