2-Chloro-5-fluoropyrimidin-4-amine → 5-Fluoro-N2-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-pyrimidine-2,4-diamine

반응식

[Cl:20][c:21]1[n:22][cH:23][c:24]([F:28])[c:25]([NH2:27])[n:26]1.[c:1]1([CH2:7][CH2:8][S:9](=[O:10])(=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][NH2:19])[CH2:16][CH2:17]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][S:9](=[O:10])(=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][NH:19][c:21]3[n:22][cH:23][c:24]([F:28])[c:25]([NH2:27])[n:26]3)[CH2:16][CH2:17]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

참가 물질

반응물 2

HCID 2543722-Chloro-5-fluoropyrimidin-4-amine

HCID 22135729[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamine

생성물 1

HCID 235772555-Fluoro-N2-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-pyrimidine-2,4-diamine

출처 및 근거

ORD 기록: ord-dc9679c80b0144a38f7985e1a536f331
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…