Water → 3-[4-[2-Amino-6-[1-(4-bromo-2-fluorophenyl)-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

HRID 1539602

반응식

[Br:7][c:8]1[cH:9][c:10]([F:20])[c:11]([CH:14]([C:15]([F:16])([F:17])[F:18])[OH:19])[cH:12][cH:13]1.[C:1](=[O:2])([O-:3])[O-:4].[CH2:49]1[O:50][CH2:51][CH2:52][O:53][CH2:54]1.[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[Cs+:5].[Cs+:6].[NH2:21][c:22]1[n:23][c:24]([Cl:47])[cH:25][c:26](-[c:28]2[cH:29][cH:30][c:31]([CH2:34][CH:35]([C:36](=[O:37])[OH:38])[NH:39][C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[cH:32][cH:33]2)[n:27]1.[OH2:48]>>[Br:7][c:8]1[cH:9][c:10]([F:20])[c:11]([CH:14]([C:15]([F:16])([F:17])[F:18])[O:19][c:24]2[n:23][c:22]([NH2:21])[n:27][c:26](-[c:28]3[cH:29][cH:30][c:31]([CH2:34][CH:35]([C:36](=[O:37])[OH:38])[NH:39][C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])[cH:32][cH:33]3)[cH:25]2)[cH:12][cH:13]1