Toluene → 2-{4-[Chloro(cyclohexyl)methyl]-5-methylfuran-2-yl}-5-fluoropyridine

반응식

[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[CH:1]1([CH:7]([OH:8])[c:9]2[c:10]([CH3:21])[o:11][c:12](-[c:14]3[n:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[S:22]([Cl:23])([Cl:24])=[O:25]>>[CH:1]1([CH:7]([c:9]2[c:10]([CH3:21])[o:11][c:12](-[c:14]3[n:15][cH:16][c:17]([F:20])[cH:18][cH:19]3)[cH:13]2)[Cl:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

참가 물질

반응물 3

HCID 1140Toluene

HCID 24386Thionyl Chloride

HCID 68515149Cyclohexyl[5-(5-fluoropyridin-2-yl)-2-methylfuran-3-yl]methanol

생성물 1

HCID 685096942-{4-[Chloro(cyclohexyl)methyl]-5-methylfuran-2-yl}-5-fluoropyridine

출처 및 근거

ORD 기록: ord-0fc9eeac37d5451880204e3f15f74bae
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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