Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Thioglycolate → Methyl 6-fluorobenzo[b]thiophene-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Thioglycolate | HCID 16907 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2,4-Difluorobenzaldehyde | HCID 73770 | — |
| 생성물 | Methyl 6-fluorobenzo[b]thiophene-2-carboxylate | HCID 57350889 | 67.3% |
반응 단계
Using 2.00 g (14.07 mmol) of 2,4-difluorobenzaldehyde, 0.84 g (21.11 mmol) of sodium hydride (60% pure) and 1.64 g (15.48 mmol) of methyl mercaptoacetate, 1.99 g of the desired product are obtained. The product is obtained in a purity which permits further reaction and is reacted without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732477B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-b5268a2b132a40b98235200a92d6471e |
| 출처 메모 | uspto-grants-2010_06 |