Dichloromethane → 4-(3-Chloro-2-fluoroanilino)-6-(piperidin-3-yloxy)-7-methoxyquinazoline

HRID 1542219

반응식

[CH2:43]([Cl:44])[Cl:45].[Cl:8][c:9]1[c:10]([F:42])[c:11]([NH:12][c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][c:19]([O:37][CH3:38])[c:20]([O:23][CH:24]4[CH2:25][N:26]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:27][CH2:28][CH2:29]4)[cH:21][c:22]23)[cH:39][cH:40][cH:41]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][c:9]1[c:10]([F:42])[c:11]([NH:12][c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][c:19]([O:37][CH3:38])[c:20]([O:23][CH:24]4[CH2:25][NH:26][CH2:27][CH2:28][CH2:29]4)[cH:21][c:22]23)[cH:39][cH:40][cH:41]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 685245814-(3-Chloro-2-fluoroanilino)-6-(1-tert-butoxycarbonylpiperidin-3-yloxy)-7-methoxyquinazoline

생성물 1

HCID 104537624-(3-Chloro-2-fluoroanilino)-6-(piperidin-3-yloxy)-7-methoxyquinazoline

출처 및 근거

ORD 기록: ord-a161ad1e41194a7a99fbde54a209fcc1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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