Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Thioglycolate → Methyl 7-bromobenzo[b]thiophene-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Thioglycolate | HCID 16907 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3-Bromo-2-fluorobenzaldehyde | HCID 22019361 | — |
| 생성물 | Methyl 7-bromobenzo[b]thiophene-2-carboxylate | HCID 18526159 | — |
반응 단계
Using 27.8 g (137.1 mmol) of 3-bromo-2-fluorobenzaldehyde, 8.2 g (205.7 mmol) of sodium hydride (60% pure) and 16.0 g (150.9 mmol) of methyl mercaptoacetate, 20.57 g of a mixture of the title compound and the corresponding acid (about 1:1) are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732477B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c70fc1add407400192318d4fd26d8681 |
| 출처 메모 | uspto-grants-2010_06 |