Tetrahydrofuran → N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-2-fluoro-5-(3-(oxazol-5-yl)pyridin-2-yloxy)benzamide

반응식

[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:23][N:24]([CH2:25][CH2:26][CH2:27][N:28]([c:29]1[c:30]([NH2:39])[cH:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]1)[CH3:40])[CH3:41].[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[cH:7][c:8]([O:11][c:12]2[n:13][cH:14][cH:15][cH:16][c:17]2-[c:18]2[cH:19][n:20][cH:21][o:22]2)[cH:9][cH:10]1>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:39][c:30]2[c:29]([N:28]([CH2:27][CH2:26][CH2:25][N:24]([CH3:23])[CH3:41])[CH3:40])[cH:34][cH:33][c:32]([C:35]([F:36])([F:37])[F:38])[cH:31]2)[cH:7][c:8]([O:11][c:12]2[n:13][cH:14][cH:15][cH:16][c:17]2-[c:18]2[cH:19][n:20][cH:21][o:22]2)[cH:9][cH:10]1