Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Thioglycolate → Methyl 5-fluoro-1-benzothiophene-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Thioglycolate | HCID 16907 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2,5-Difluorobenzaldehyde | HCID 137663 | — |
| 생성물 | Methyl 5-fluoro-1-benzothiophene-2-carboxylate | HCID 22473847 | — |
반응 단계
Using 5.0 g (35.2 mmol) of 2,5-difluorobenzaldehyde, 2.11 g (52.78 mmol) of sodium hydride (60% pure) and 4.11 g (38.7 mmol) of methyl mercaptoacetate, 1.1 g (14.3% of theory) of the title compound are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732477B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-28aaadee87cc4a78bb55ccfaafe7e468 |
| 출처 메모 | uspto-grants-2010_06 |