{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → {1-[4-(7-Methoxy-4-oxo-2-phenyl-4H-pyrano[2,3-b]pyridin-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36].[I:37][c:38]1[c:39](=[O:56])[c:40]2[c:41]([n:42][c:43]([O:46][CH3:47])[cH:44][cH:45]2)[o:48][c:49]1-[c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:38]3[c:39](=[O:56])[c:40]4[c:41]([n:42][c:43]([O:46][CH3:47])[cH:44][cH:45]4)[o:48][c:49]3-[c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]

참가 물질

반응물 2

HCID 67067635{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester

HCID 670676803-Iodo-7-methoxy-2-phenyl-pyrano[2,3-b]pyridin-4-one

생성물 1

HCID 68227637{1-[4-(7-Methoxy-4-oxo-2-phenyl-4H-pyrano[2,3-b]pyridin-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-81a683eebba44bc1a9d84511b9031eaa
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…