2-(2,5-Dichloro-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide → 2-{5-Chloro-2-[3-(2-fluoro-1-fluoromethyl-ethyl)-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-N,N-dimethyl-benzenesulfonamide
반응식
[Cl:20][c:21]1[n:22][cH:23][c:24]([Cl:40])[c:25]([NH:27][c:28]2[c:29]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:30][cH:31][cH:32][cH:33]2)[n:26]1.[F:1][CH2:2][CH:3]([CH2:4][F:5])[N:6]1[CH2:7][CH2:8][c:9]2[c:10]([cH:13][c:14]([NH2:19])[c:15]([O:17][CH3:18])[cH:16]2)[CH2:11][CH2:12]1>>[F:1][CH2:2][CH:3]([CH2:4][F:5])[N:6]1[CH2:7][CH2:8][c:9]2[c:10]([cH:13][c:14]([NH:19][c:21]3[n:22][cH:23][c:24]([Cl:40])[c:25]([NH:27][c:28]4[c:29]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:30][cH:31][cH:32][cH:33]4)[n:26]3)[c:15]([O:17][CH3:18])[cH:16]2)[CH2:11][CH2:12]1참가 물질
3
반응물 2
생성물 1
출처 및 근거
- ORD 기록
- ord-61a206def3f4463f948bb751702b0a4c
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)