1-Methyl-4-piperidone → 4-Hydroxy-4-(alpha-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidine

반응식

[Br:1][c:2]1[c:3]([CH2:4][OH:5])[cH:6][cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1.[CH3:14][N:15]1[CH2:16][CH2:17][C:18](=[O:21])[CH2:19][CH2:20]1>>[c:2]1([C:18]2([OH:21])[CH2:17][CH2:16][N:15]([CH3:14])[CH2:20][CH2:19]2)[c:3]([CH2:4][OH:5])[cH:6][cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1

참가 물질

반응물 2

HCID 740491-Methyl-4-piperidone

HCID 2779289[2-Bromo-4-(trifluoromethyl)phenyl]methanol

생성물 1

HCID 867335264-Hydroxy-4-(alpha-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidine

출처 및 근거

ORD 기록: ord-f11c3d7d8cea40b18c5ff372975fce68
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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