Dichloromethane → 2-[4-(Methylsulfonyl)phenyl]-5-[(4-piperidinylmethyl)oxy]pyridine

반응식

[CH3:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15](-[c:18]2[cH:19][cH:20][c:21]([O:24][CH2:25][CH:26]3[CH2:27][CH2:28][N:29]([C:32]([O:33][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38])[CH2:30][CH2:31]3)[cH:22][n:23]2)[cH:16][cH:17]1.[Cl:39][CH2:40][Cl:41].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[CH3:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][cH:14][c:15](-[c:18]2[cH:19][cH:20][c:21]([O:24][CH2:25][CH:26]3[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]3)[cH:22][n:23]2)[cH:16][cH:17]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 249943331,1-Dimethylethyl 4-[({6-[4-(methylsulfonyl)phenyl]-3-pyridinyl}oxy)methyl]-1-piperidinecarboxylate

생성물 1

HCID 597185862-[4-(Methylsulfonyl)phenyl]-5-[(4-piperidinylmethyl)oxy]pyridine

출처 및 근거

ORD 기록: ord-8fe023886a3b4ac38c77b1ddf76403a0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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