5-bromo-N-(2-methylbenzyl)nicotinamide → Tert-butyl 1-[5-[(2-methylphenyl)methylcarbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

반응식

[Br:16][c:17]1[cH:18][n:19][cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][c:26]2[c:27]([CH3:32])[cH:28][cH:29][cH:30][cH:31]2)[cH:33]1.[NH:1]1[CH:2]2[CH:3]([CH2:4][CH2:5]1)[CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]2>>[N:1]1([c:17]2[cH:18][n:19][cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][c:26]3[c:27]([CH3:32])[cH:28][cH:29][cH:30][cH:31]3)[cH:33]2)[CH:2]2[CH:3]([CH2:4][CH2:5]1)[CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]2

참가 물질

반응물 2

HCID 91046105-bromo-N-(2-methylbenzyl)nicotinamide

HCID 225622051,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate

생성물 1

HCID 67265847Tert-butyl 1-[5-[(2-methylphenyl)methylcarbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

출처 및 근거

ORD 기록: ord-8737aae95ed54cd1aff0cce46dc0ab1c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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