Toluene → Tert-butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate

반응식

[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]1.[CH3:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1>>[c:2]1([N:19]2[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:21][CH2:20]2)[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1

참가 물질

반응물 3

HCID 1140Toluene

HCID 775312,4-Dichloropyrimidine

HCID 114013941-Boc-4-methylpiperazine

생성물 1

HCID 46738270Tert-butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate

출처 및 근거

ORD 기록: ord-1d4e369876284a1bbaf4c119d7daa39f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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