9-Ethyl-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-2-ylamine → 2-[5-Chloro-2-(9-ethyl-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-benzamide

반응식

[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][CH2:6][O:7][c:8]2[c:9]1[cH:10][c:11]([NH2:14])[cH:12][cH:13]2.[Cl:15][c:16]1[n:17][cH:18][c:19]([Cl:40])[c:20]([NH:22][c:23]2[c:24]([C:25](=[O:26])[NH:27][CH3:28])[cH:29][c:30](-[c:34]3[cH:35][n:36][n:37]([CH3:39])[cH:38]3)[cH:31][c:32]2[F:33])[n:21]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][CH2:6][O:7][c:8]2[c:9]1[cH:10][c:11]([NH:14][c:16]1[n:17][cH:18][c:19]([Cl:40])[c:20]([NH:22][c:23]3[c:24]([C:25](=[O:26])[NH:27][CH3:28])[cH:29][c:30](-[c:34]4[cH:35][n:36][n:37]([CH3:39])[cH:38]4)[cH:31][c:32]3[F:33])[n:21]1)[cH:12][cH:13]2