Methyl 4-(bromomethyl)benzoate → 4-{5-Chloro-2-[1-(3-chloro-benzyl)-5,6-difluoro-1H-benzoimidazol-2-yl]-phenoxymethyl}-benzoic acid methyl ester

반응식

[CH3:28][O:29][C:30]([c:31]1[cH:32][cH:33][c:34]([CH2:37][Br:38])[cH:35][cH:36]1)=[O:39].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][c:15]2[cH:16][c:17]([Cl:21])[cH:18][cH:19][cH:20]2)[cH:22][c:23]([F:27])[c:24]([F:26])[cH:25]3)[c:6]([OH:8])[cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][c:15]2[cH:16][c:17]([Cl:21])[cH:18][cH:19][cH:20]2)[cH:22][c:23]([F:27])[c:24]([F:26])[cH:25]3)[c:6]([O:8][CH2:37][c:34]2[cH:33][cH:32][c:31]([C:30]([O:29][CH3:28])=[O:39])[cH:36][cH:35]2)[cH:7]1

참가 물질

반응물 2

HCID 256687Methyl 4-(bromomethyl)benzoate

HCID 1363784805-chloro-2-[1-(3-chloro-benzyl)-5,6-difluoro-1H-benzoimidazol-2-yl]-phenol

생성물 1

HCID 670500304-{5-Chloro-2-[1-(3-chloro-benzyl)-5,6-difluoro-1H-benzoimidazol-2-yl]-phenoxymethyl}-benzoic acid methyl ester

출처 및 근거

ORD 기록: ord-ee0ba9d489b846ad8df72f4599869e8e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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