돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 15595생성일: 2026년 10월 25일

Trifluoroacetic acid → HCID 59342516, 화합물

https://huagongshe.com/reaction/15595

반응식

참여 물질

역할이름HCID투입량
반응물Trifluoroacetic acidHCID 6422—
반응물{5-[Benzyl-(3-fluoro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl esterHCID 67201621—
생성물HCID 59342516HCID 59342516—

반응 단계

{5-[Benzyl-(3-fluoro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl ester (0.12 mmol) was treated with TFA (2 mL) for 2 hours, concentrated, and purified by preparative LCMS to give the title compound. 1H NMR (d6-DMSO) δ7.79 (m, 1H), 7.68 (m, 1H), 7.55 (m, 2H), 7.21 (m, 6H), 7.02 (m, 1H), 6.92 (m, 1H), 5.11 (s, 2H), 4.99 (s, 2H), 2.68 (t, 2H), 1.71 (m, 2H), 0.95 (t, 3H). MS calculated for C26H24FN3O3+H: 446, observed: 446.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07732618B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-bc462ef2e14e4e7f8fd81cd156a4882d
출처 메모uspto-grants-2010_06