Dichloromethane → 2-(2-(2-(piperidin-3-yl)-1H-benzo[d]imidazol-1-yl)ethyl)isoindoline-1,3-dione

반응식

[Cl:43][CH2:44][Cl:45].[O:1]=[C:2]1[N:3]([CH2:12][CH2:13][n:14]2[c:15]([CH:23]3[CH2:24][N:25]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:26][CH2:27][CH2:28]3)[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[O:1]=[C:2]1[N:3]([CH2:12][CH2:13][n:14]2[c:15]([CH:23]3[CH2:24][NH:25][CH2:26][CH2:27][CH2:28]3)[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 66786754tert-butyl 3-(1-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

생성물 1

HCID 667869112-(2-(2-(piperidin-3-yl)-1H-benzo[d]imidazol-1-yl)ethyl)isoindoline-1,3-dione

출처 및 근거

ORD 기록: ord-d9f379efd415484096583e3edee4f1c0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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