Tetrahydrofuran → Tert-butyl 4-(6-(2-fluoro-5-methylnicotinoyl)pyridin-2-yl)-1,4-diazepane-1-carboxylate

HRID 1563442

반응식

HRID 1563442 반응식
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[n:7]1.[F:22][c:23]1[c:24]([C:25](=[O:26])[N:27]([O:28][CH3:29])[CH3:30])[cH:31][c:32]([CH3:35])[cH:33][n:34]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[c:2]1([C:25]([c:24]2[c:23]([F:22])[n:34][cH:33][c:32]([CH3:35])[cH:31]2)=[O:26])[cH:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[n:7]1

참가 물질

4

반응물 3

HCID 8028TetrahydrofuranHCID 576904762-fluoro-N-methoxy-N,5-dimethylnicotinamideHCID 70700340tert-Butyl 4-(6-bromopyridin-2-yl)-1,4-diazepane-1-carboxylate

생성물 1

HCID 57690501Tert-butyl 4-(6-(2-fluoro-5-methylnicotinoyl)pyridin-2-yl)-1,4-diazepane-1-carboxylate

출처 및 근거

ORD 기록
ord-2b5822c853cc42428cc2277cc1df1fb9
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

연결된 노트

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