5-Bromo-2,4-difluorobenzenesulfonamide → 2,4-Difluoro-5-[4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-imidazo[1,5-a]pyrimidin-8-ylethynyl]-benzenesulfonamide

반응식

[Br:26][c:27]1[c:28]([F:38])[cH:29][c:30]([F:37])[c:31]([S:33](=[O:34])(=[O:35])[NH2:36])[cH:32]1.[C:1](#[CH:2])[c:3]1[n:4][cH:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]>>[C:1](#[C:2][c:27]1[c:28]([F:38])[cH:29][c:30]([F:37])[c:31]([S:33](=[O:34])(=[O:35])[NH2:36])[cH:32]1)[c:3]1[n:4][cH:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]

참가 물질

반응물 2

HCID 27732955-Bromo-2,4-difluorobenzenesulfonamide

HCID 866080858-Ethynyl-4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-imidazo[1,5-a]pyrimidine

생성물 1

HCID 167359562,4-Difluoro-5-[4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-imidazo[1,5-a]pyrimidin-8-ylethynyl]-benzenesulfonamide

출처 및 근거

ORD 기록: ord-3f1d1e3a2571468795329815d65f258b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

반응 노트

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