Pyridine → N-[4-chloro-2-fluoro-5-[[2-(3-phenylprop-2-enoylamino)-[1,3]thiazolo[5,4-b]pyridin-5-yl]oxy]phenyl]-3-(2-cyanopropan-2-yl)benzamide

HRID 1564853

반응식

[CH3:34][C:35]([N:36]([CH3:37])[CH3:38])=[O:39].[CH3:57][CH2:58][O:59][C:60](=[O:61])[CH3:62].[NH2:1][c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[c:13]([Cl:33])[cH:14][c:15]([F:32])[c:16]([NH:18][C:19]([c:20]4[cH:21][c:22]([C:26]([CH3:27])([CH3:28])[C:29]#[N:30])[cH:23][cH:24][cH:25]4)=[O:31])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1.[c:40]1([CH:46]=[CH:47][C:48](=[O:49])[Cl:50])[cH:41][cH:42][cH:43][cH:44][cH:45]1.[cH:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1>>[NH:1]([c:2]1[s:3][c:4]2[n:5][c:6]([O:11][c:12]3[c:13]([Cl:33])[cH:14][c:15]([F:32])[c:16]([NH:18][C:19]([c:20]4[cH:21][c:22]([C:26]([CH3:27])([CH3:28])[C:29]#[N:30])[cH:23][cH:24][cH:25]4)=[O:31])[cH:17]3)[cH:7][cH:8][c:9]2[n:10]1)[C:48]([CH:47]=[CH:46][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)=[O:49]