1-Bromo-4-fluorobenzene → (1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl)-(4-fluoro-phenyl)-methanone

반응식

[Br:26][c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[n:7][cH:8][n:9](-[c:11]2[cH:12][c:13](-[c:17]3[c:18]([F:24])[n:19][cH:20][cH:21][c:22]3[F:23])[cH:14][cH:15][cH:16]2)[cH:10]1)[CH3:25]>>[C:4](=[O:5])([c:6]1[n:7][cH:8][n:9](-[c:11]2[cH:12][c:13](-[c:17]3[c:18]([F:24])[n:19][cH:20][cH:21][c:22]3[F:23])[cH:14][cH:15][cH:16]2)[cH:10]1)[c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1

참가 물질

반응물 2

HCID 99931-Bromo-4-fluorobenzene

HCID 866344341-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazole-4-carboxylic acid methoxy-methyl-amide

생성물 1

HCID 67429480(1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl)-(4-fluoro-phenyl)-methanone

출처 및 근거

ORD 기록: ord-1a2868ad89d34076984a996a37162fbd
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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