4-Fluoro-2-(trifluoromethyl)benzoyl chloride → 6-[4-(4-FLUORO-2-TRIFLUOROMETHYLBENZOYL)PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXYLIC Acid (3-CYCLOPROPYLPROPYL)AMIDE

반응식

[CH:15]1([CH2:18][CH2:19][CH2:20][NH:21][C:22](=[O:23])[c:24]2[n:25][n:26][c:27]([N:30]3[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]3)[cH:28][cH:29]2)[CH2:16][CH2:17]1.[F:1][c:2]1[cH:3][c:4]([C:11]([F:12])([F:13])[F:14])[c:5]([C:6](=[O:7])[Cl:8])[cH:9][cH:10]1>>[F:1][c:2]1[cH:3][c:4]([C:11]([F:12])([F:13])[F:14])[c:5]([C:6](=[O:7])[N:33]2[CH2:32][CH2:31][N:30]([c:27]3[n:26][n:25][c:24]([C:22]([NH:21][CH2:20][CH2:19][CH2:18][CH:15]4[CH2:16][CH2:17]4)=[O:23])[cH:29][cH:28]3)[CH2:35][CH2:34]2)[cH:9][cH:10]1

참가 물질

반응물 2

HCID 6056804-Fluoro-2-(trifluoromethyl)benzoyl chloride

HCID 668493796-Piperazin-1-yl-pyridazine-3-carboxylic acid (3-cyclopropylpropyl)amide

생성물 1

HCID 114202126-[4-(4-FLUORO-2-TRIFLUOROMETHYLBENZOYL)PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXYLIC Acid (3-CYCLOPROPYLPROPYL)AMIDE

출처 및 근거

ORD 기록: ord-69a0d197a43341248de412c8c492e770
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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