Dichloromethane → 7-(Isobutyl-methyl-amino)-4-[3-(3-methyl-isoxazol-5-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

반응식

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:24][C:25]([CH2:26][C:27](=[O:5])[c:29]2[cH:30][c:31](-[c:35]3[cH:36][c:37]([CH3:40])[n:38][o:39]3)[cH:32][cH:33][cH:34]2)=[O:41])[cH:10][c:11]([C:20]([F:21])([F:22])[F:23])[c:12]([N:14]([CH3:15])[CH2:16][CH:17]([CH3:18])[CH3:19])[cH:13]1)([CH3:6])([CH3:28])[CH3:42].[Cl:50][CH2:51][Cl:52].[F:43][C:44]([F:45])([F:46])[C:47]([OH:48])=[O:49]>>[N:7]1=[C:27]([c:29]2[cH:30][c:31](-[c:35]3[cH:36][c:37]([CH3:40])[n:38][o:39]3)[cH:32][cH:33][cH:34]2)[CH2:26][C:25](=[O:41])[NH:24][c:9]2[c:8]1[cH:13][c:12]([N:14]([CH3:15])[CH2:16][CH:17]([CH3:18])[CH3:19])[c:11]([C:20]([F:21])([F:22])[F:23])[cH:10]2