4-(4-Methylpiperazin-1-yl)aniline → 6-Bromo-8-ethyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([S:10]([CH3:11])=[O:12])[n:8][cH:9]2)[n:13]([CH2:16][CH3:17])[c:14]1=[O:15].[CH3:18][N:19]1[CH2:20][CH2:21][N:22]([c:25]2[cH:26][cH:27][c:28]([NH2:29])[cH:30][cH:31]2)[CH2:23][CH2:24]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([NH:29][c:28]3[cH:27][cH:26][c:25]([N:22]4[CH2:21][CH2:20][N:19]([CH3:18])[CH2:24][CH2:23]4)[cH:31][cH:30]3)[n:8][cH:9]2)[n:13]([CH2:16][CH3:17])[c:14]1=[O:15]

참가 물질

반응물 2

HCID 7372534-(4-Methylpiperazin-1-yl)aniline

HCID 671196106-Bromo-8-ethyl-2-methylsulfinylpyrido[2,3-d]pyrimidin-7-one

생성물 1

HCID 667604546-Bromo-8-ethyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one

출처 및 근거

ORD 기록: ord-718d7211974644f9b15d89f01caac504
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

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