Dimethylformamide → 1-[3-[(N-Benzyl pyrrolidin-3-yl)carbamoyl]phenylcarbamoyl]-5-methylthio-6-trifluoromethyl indoline

HRID 1571545노트

반응식

[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:1][S:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][c:11]1[C:12]([F:13])([F:14])[F:15])[N:8]([C:16]([NH:17][c:18]1[cH:19][c:20]([C:24](=[O:25])[OH:26])[cH:21][cH:22][cH:23]1)=[O:27])[CH2:7][CH2:6]2.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl:28][C:29]([C:30]([Cl:31])=[O:32])=[O:33].[Cl:54][CH2:55][Cl:56].[NH2:41][CH:42]1[CH2:43][N:44]([CH2:47][c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[CH2:45][CH2:46]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66]>>[CH3:1][S:2][c:3]1[cH:4][c:5]2[c:9]([cH:10][c:11]1[C:12]([F:13])([F:14])[F:15])[N:8]([C:16]([NH:17][c:18]1[cH:19][c:20]([C:24](=[O:25])[NH:41][CH:42]3[CH2:43][N:44]([CH2:47][c:48]4[cH:49][cH:50][cH:51][cH:52][cH:53]4)[CH2:45][CH2:46]3)[cH:21][cH:22][cH:23]1)=[O:27])[CH2:7][CH2:6]2