Tetrahydrofuran → (4-Bromo-phenyl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-yl)methanone

반응식

[NH:18]1[CH:19]([CH2:23][N:24]2[CH2:25][CH2:26][CH2:27][CH2:28]2)[CH2:20][CH2:21][CH2:22]1.[O:1]=[C:2]1[CH2:3][CH2:4][C:5](=[O:6])[N:7]1[O:8][C:9]([c:10]1[cH:11][cH:12][c:13]([Br:16])[cH:14][cH:15]1)=[O:17].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[C:9]([c:10]1[cH:11][cH:12][c:13]([Br:16])[cH:14][cH:15]1)(=[O:17])[N:18]1[CH:19]([CH2:23][N:24]2[CH2:25][CH2:26][CH2:27][CH2:28]2)[CH2:20][CH2:21][CH2:22]1

참가 물질

반응물 3

HCID 8028Tetrahydrofuran

HCID 1428252-(Pyrrolidin-1-ylmethyl)pyrrolidine

HCID 138964302,5-Dioxopyrrolidin-1-yl 4-bromobenzoate

생성물 1

HCID 11964813(4-Bromo-phenyl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-yl)methanone

출처 및 근거

ORD 기록: ord-cf78358bc48f44d590e041d8c111187a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…