Methanol → Methyl 7-methyl-9H-xanthene-2-carboxylate

HRID 1576135노트

반응식

HRID 1576135 반응식
[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([OH:18])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1.[CH3:19]O.S(=O)(=O)(O)O>O>[CH3:1][C:2]1[CH:15]=[C:14]2[C:5]([O:6][C:7]3[CH:8]=[CH:9][C:10]([C:16]([O:18][CH3:19])=[O:17])=[CH:11][C:12]=3[CH2:13]2)=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 215006717-Methyl-9H-xanthene-2-carboxylic acid

생성물 1

HCID 21500836Methyl 7-methyl-9H-xanthene-2-carboxylate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Twenty-six grams of 7-methylxanthene-2-carboxylic acid is added to 400 ml. of absolute methanol. To the resultant solution are added 18 ml. of concentrated sulfuric acid and the mixture is then heated at reflux for about two hours. The mixture is then cooled to 40° and sufficient water is added to bring the total volume to 1400 ml. The resultant mixture is then filtered to give methyl 7-methylxanthene-2-carboxylate.

후처리

  1. temperatureat reflux for about two hours
  2. temperatureThe mixture is then cooled to 40°
  3. filtrationThe resultant mixture is then filtered

출처 및 근거

ORD 기록
ord-e517ac80cacc4e97bfa952cb8d6313b0
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03979414

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