Acetic Acid → HCID 86734028, 화합물

HRID 1576780노트

반응식

HRID 1576780 반응식
[CH2:1]([O:3][C@H:4]1[CH2:29][C@@:28]2([CH3:30])[C@@H:7]([CH2:8][CH2:9][C@@H:10]3[C@@H:27]2[C:26](=[O:31])[CH2:25][C@@:24]2([CH3:32])[C@H:11]3[CH2:12][CH2:13][C@@H:14]2[C:15](=[O:23])[CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH2:6][C@@H:5]1[OH:33])[CH3:2].[C:34]([OH:37])(=[O:36])[CH3:35]>C(O)C>[C:34]([OH:37])(=[O:36])[CH3:35].[CH2:1]([O:3][C@H:4]1[CH2:29][C@@:28]2([CH3:30])[C@@H:7]([CH2:8][CH2:9][C@@H:10]3[C@@H:27]2[C:26](=[O:31])[CH2:25][C@@:24]2([CH3:32])[C@H:11]3[CH2:12][CH2:13][C@@H:14]2[C:15](=[O:23])[CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH2:6][C@@H:5]1[OH:33])[CH3:2]

참가 물질

4

반응물 2

HCID 176Acetic AcidHCID 86734023HCID 86734023, 화합물

생성물 1

HCID 86734028HCID 86734028, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 2β-ethoxy-3α-hydroxy-21-morpholino-5α-pregnane-11,20-dione (116 mg., 0.25 mmole) in ethanol (2 ml.) was treated with 0.1N aqueous acetic acid (2.5 ml. 0.25 mmole) and the resulting solution was evaporated under vacuum. The residue was treated with water (ca 1 ml.) and the undissolved solid (66 mg.) was removed by filtration. The filtrate was diluted to 5 ml. with distilled water, thereby giving a 1% aqueous solution of the title compound.

후처리

  1. customthe resulting solution was evaporated under vacuum
  2. additionThe residue was treated with water (ca 1 ml.)
  3. customthe undissolved solid (66 mg.) was removed by filtration
  4. additionThe filtrate was diluted to 5 ml

출처 및 근거

ORD 기록
ord-899a9718125a4c7b83e44bf443dcac5c
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03983111

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