2,6-Xylyl isocyanate → N-(1,3-Dimethyl-4-oxoimidazolidin-2-ylidene)-N'-(2,6-dimethylphenyl)urea

HRID 1576837

반응식

HRID 1576837 반응식
[CH3:1][N:2]1[CH2:6][C:5](=[O:7])[N:4]([CH3:8])[C:3]1=[NH:9].[CH3:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH3:17])[C:12]=1[N:18]=[C:19]=[O:20]>O1CCCC1>[CH3:1][N:2]1[CH2:6][C:5](=[O:7])[N:4]([CH3:8])[C:3]1=[N:9][C:19]([NH:18][C:12]1[C:11]([CH3:10])=[CH:16][CH:15]=[CH:14][C:13]=1[CH3:17])=[O:20]

참가 물질

4

반응물 2

HCID 987872,6-Xylyl isocyanateHCID 140604272-Imino-1,3-dimethylimidazolidin-4-one

생성물 1

HCID 54230876N-(1,3-Dimethyl-4-oxoimidazolidin-2-ylidene)-N'-(2,6-dimethylphenyl)urea

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A mixture of 6.35 g (0.050 mole) of 1,3-dimethyl-2-iminoimidazolidin-4-one and 7.25 g (0.050 mole) of 2,6-dimethylphenylisocyanate in 75 ml. of dry tetrahydrofuran is stirred at room temperature for two hours followed by refluxing it for thirty minutes. The reaction mixture is evaporated in vacuo to give a solid, which is crystallized from tetrahydrofuran-ether. Two more recrystallizations from the same solvent mixture gives pure product, 1-(1,3-dimethyl-4-oxo-2-imidazolidinylidene)-3-(2,6-dimethylphenyl) urea; m.p. 115.5°-118.5°C.

후처리

  1. temperatureby refluxing it for thirty minutes
  2. customThe reaction mixture is evaporated in vacuo
  3. customto give a solid, which
  4. customis crystallized from tetrahydrofuran-ether
  5. customTwo more recrystallizations from the same solvent mixture

출처 및 근거

ORD 기록
ord-12b6665c574c4cdba7d9f873b7be165b
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03983135

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