Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1S,2R)-(+)-Norephedrine → alpha-[1-(2-Imidazolin-2-ylamino)ethyl]benzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1S,2R)-(+)-Norephedrine | HCID 4786 | — |
| 반응물 | O-Xylene | HCID 7237 | — |
| 반응물 | 2-Nitroamino-2-imidazoline | HCID 410042 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | alpha-[1-(2-Imidazolin-2-ylamino)ethyl]benzyl alcohol | HCID 54133258 | — |
반응 단계
A mixture of 6.5 parts of α-(1-aminoethyl)benzyl alcohol (also known as morephedrine), 5.2 parts of 2-(nitramino)-2-imidazoline and 8 parts of xylene is stirred for 30 minutes while heating at 160°-170°C. The reaction mixture is cooled and diluted with acetone. The latter is removed in vacuo, yielding α-[1-(2-imidazolin-2-ylamino)-ethyl]benzyl alcohol as an oily residue.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03983133 |
| 출처 데이터셋 | uspto-grants-1976_09 |
| ORD ID | ord-7b3aeac0763840eb994f97a3f570e980 |
| 출처 메모 | uspto-grants-1976_09 |