Glycol monoethyl ether → 2-(2-Ethoxyethoxy)-N,N-bis[2-(2-ethoxyethoxy)ethyl]ethan-1-amine

HRID 1577492

반응식

HRID 1577492 반응식
Cl.Cl[CH2:3][CH2:4][N:5]([CH2:9][CH2:10]Cl)[CH2:6][CH2:7]Cl.[CH2:12]([O:14][CH2:15][CH2:16][OH:17])[CH3:13]>>[CH2:4]([N:5]([CH2:9][CH2:10][O:17][CH2:16][CH2:15][O:14][CH2:12][CH3:13])[CH2:6][CH2:7][O:17][CH2:16][CH2:15][O:14][CH2:12][CH3:13])[CH2:3][O:17][CH2:16][CH2:15][O:14][CH2:12][CH3:13]

참가 물질

3

반응물 2

HCID 8076Glycol monoethyl etherHCID 61220Tris(2-chloroethyl)amine hydrochloride

생성물 1

HCID 30186232-(2-Ethoxyethoxy)-N,N-bis[2-(2-ethoxyethoxy)ethyl]ethan-1-amine수율 68%

실험 절차

51.6 g (i.e., 0.215 mol) of tris-(2-chloroethyl)-amine hydrochloride were added to the above mixture (a). The mixture was subsequently heated at the reflux temperature of the 2-ethoxyethanol for 12 hours and the solvent was then distilled under reduced pressure. The excess sodium 2-ethoxyethanolate was neutralized by adding 12 cm3 of aqueous HCl (10 N) thereto. The sodium chloride was filtered off and the solution was distilled. The tris-(3,6-dioxaoctyl)-amine distilled between 200° C. and 210° C. under a pressure of 1 mm Hg. The yield was 68%.

후처리

  1. distillationthe solvent was then distilled under reduced pressure
  2. additionby adding 12 cm3 of aqueous HCl (10 N)
  3. filtrationThe sodium chloride was filtered off
  4. distillationthe solution was distilled
  5. distillationThe tris-(3,6-dioxaoctyl)-amine distilled between 200° C. and 210° C. under a pressure of 1 mm Hg

출처 및 근거

ORD 기록
ord-5ca93669df874129a341432824b7b7da
출처 데이터셋
uspto-grants-1981_09
특허 번호
US04288386

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