Isopropylamine → HCID 178457124, 화합물

HRID 1577540

반응식

[C:1]([C:9]1[S:13][C:12]2[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=2[C:10]=1[OH:18])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)(Cl)Cl.[CH:25]([NH2:28])([CH3:27])[CH3:26]>>[CH3:26][CH:25]([NH:28]/[C:1](/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[C:9]1\[C:10](=[O:18])[C:11]2[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=2[S:13]\1)[CH3:27]

참가 물질

반응물 3

HCID 6363Isopropylamine

HCID 24819Phosphorus pentachloride

HCID 4712192Methanone, (3-hydroxybenzo[b]thien-2-yl)phenyl-

생성물 1

HCID 178457124HCID 178457124, 화합물수율 54%

실험 절차

Prepared as in Example 1 from 2-benzoyl-benzo[b]thiophen-3-ol, phosphorus(V) chloride and an aqueous 38.5% isopropylamine solution with a yield of 54% of theory. M.P. 112°-113° C. (ethyl acetate/petroleum ether 1:1).

출처 및 근거

ORD 기록: ord-e0788fceaf0b4eb5996681857f85280e
출처 데이터셋: uspto-grants-1981_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04288437

연결된 노트

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