Acetic Acid → 3-(2,2-Dichlorovinyloxy)-benzaldehyde

HRID 1578124노트

반응식

HRID 1578124 반응식
[Cl:1][C:2]([Cl:13])=[CH:3][O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH2:8]Br.C1N2CN3CN(C2)CN1C3.C(O)(=[O:26])C>O>[Cl:1][C:2]([Cl:13])=[CH:3][O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][CH:12]=1)[CH:8]=[O:26]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 4101HexamethylenetetramineHCID 204827061-(Bromomethyl)-3-[(2,2-dichloroethenyl)oxy]benzene

생성물 1

HCID 134899763-(2,2-Dichlorovinyloxy)-benzaldehyde

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of 8.5 g of 3-(2,2-dichlorovinyloxy)-benzyl bromide in 12.6 ml of acetic acid and 12.6 ml of water are added 8.4 g of hexamethylene tetramine. The resultant solution is refluxed for two hours. Subsequently 10 ml of HC1 are added and the reaction mixture is stirred for half an hour at 100°-110° C. The solution is washed with 100 ml of water and extracted cold (3 times) with 100 ml of ethyl acetate. The extract is washed with sodium carbonate solution and evaporated, to yield 5.8 g of 3-(2,2-dichlorovinyloxy)-benzaldehyde as a yellowish-brown oil, which can be used without further purification.

후처리

  1. additionSubsequently 10 ml of HC1 are added
  2. washThe solution is washed with 100 ml of water
  3. extractionextracted cold (3 times) with 100 ml of ethyl acetate
  4. washThe extract is washed with sodium carbonate solution
  5. customevaporated

출처 및 근거

ORD 기록
ord-7fe54801ba4f4bdbbb6f73b7ff4eab5f
출처 데이터셋
uspto-grants-1981_09
특허 번호
US04291056

반응 노트

불러오는 중…