Acetone → HCID 12760709, 화합물

HRID 1578179노트

반응식

HRID 1578179 반응식
[OH:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[C:3]([OH:5])=[O:4].[CH3:15][C:16]([CH3:18])=O.S(=O)(=O)(O)O.C(=O)([O-])[O-].[Na+].[Na+]>O>[C:12]([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:2]1[C:3](=[O:5])[O:4][C:16]([CH3:18])([CH3:15])[O:1]1)([OH:14])=[O:13]

참가 물질

6

반응물 4

HCID 180AcetoneHCID 1118Sulfuric AcidHCID 10340Sodium CarbonateHCID 127607082-Hydroxynonanedioic acid

생성물 1

HCID 12760709HCID 12760709, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A stirred mixture of 10.2 g. of 2-hydroxynonanedioic acid, 50 ml. of acetone, 75 ml. of petroleum ether (b.p. 30°-55° C.), and 0.25 ml. of sulfuric acid is heated at reflux for 7 hours with azeotropic removal of water. The stirred mixture is treated with 0.59 g. of sodium carbonate and diluted with petroleum ether. The solution is decanted from solid and concentrated to give 9.4 g. of oil; pmr (CDCl3) δ1.58 and 1.63 (gem-dimethyl group).

후처리

  1. additionA stirred mixture of 10.2 g
  2. additionThe stirred mixture is treated with 0.59 g
  3. customThe solution is decanted from solid
  4. concentrationconcentrated
  5. customto give 9.4 g

출처 및 근거

ORD 기록
ord-eab0944238054f6e95ce3e74316fc341
출처 데이터셋
uspto-grants-1981_09
특허 번호
US04291175

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