4-Fluoro-3-(3-cyanopyridin-2-yl)phenylboronic acid → 2-[2-Fluoro-5-(7-trifluoromethyl[1,8]naphthyridin-4-yl)phenyl]nicotinonitrile

HRID 157823

반응식

HRID 157823 반응식
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1.[F:16][c:17]1[c:18](-[c:26]2[n:27][cH:28][cH:29][cH:30][c:31]2[C:32]#[N:33])[cH:19][c:20]([B:23]([OH:24])[OH:25])[cH:21][cH:22]1>>[c:2]1(-[c:20]2[cH:19][c:18](-[c:26]3[n:27][cH:28][cH:29][cH:30][c:31]3[C:32]#[N:33])[c:17]([F:16])[cH:22][cH:21]2)[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1

참가 물질

3

반응물 2

HCID 222852704-Fluoro-3-(3-cyanopyridin-2-yl)phenylboronic acidHCID 222852765-chloro-2-(trifluoromethyl)-1,8-Naphthyridine

생성물 1

HCID 102719302-[2-Fluoro-5-(7-trifluoromethyl[1,8]naphthyridin-4-yl)phenyl]nicotinonitrile

출처 및 근거

ORD 기록
ord-baf6a23bd58d4400bac20a5d99c8c74b
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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