Water → HCID 54181831, 화합물
반응식
[CH3:1][CH:2]([OH:17])[C:3]1[O:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.O>[Pd].CO>[CH3:1][CH:2]([OH:17])[C:3]1[O:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1참가 물질
5
실험 절차
A mixture of 79 g (0.34 mole) of the compound of Example I, 1 tsp. of 5% Pd/C, 50% H2O, and 500 ml of methanol was shaken under hydrogen pressure with the theoretical amount of H2 being absorbed. The catalyst was removed by filtration, and the filtrate was taken to near dryness on a Calab evaporator. The resulting solid was filtered and air-dried to yield 49 g (71%) of title compound. An analytical sample was prepared by recrystallizing a sample twice from ethanol/charcoal, m.p. 100°-104°.
후처리
- customabsorbed
- customThe catalyst was removed by filtration
- customon a Calab evaporator
- filtrationThe resulting solid was filtered
- customair-dried
출처 및 근거
- ORD 기록
- ord-33b955db45094f47a9e950065cea1364
- 출처 데이터셋
- uspto-grants-1976_01
- 특허 번호
- US03931247
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