Sulfuric Acid → HCID 10198445, 화합물

HRID 1579847노트

반응식

HRID 1579847 반응식
[O:1]=[C:2]1[C:6](=O)[CH2:5][C:4](=[O:8])[CH:3]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16].S(=O)(=O)(O)O.[H][H]>[Pd].C(O)(=O)C>[O:1]=[C:2]1[CH2:6][CH2:5][C:4](=[O:8])[CH:3]1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16]

참가 물질

6

반응물 3

HCID 1118Sulfuric AcidHCID 19367748HCID 19367748, 화합물HCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 10198445HCID 10198445, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 176Acetic Acid용매

실험 절차

A mixture containing 45.7 parts of 2,3,5-trioxocyclopentaneheptanoic acid, 13 parts of 5% palladium-on-carbon catalyst, 453 parts of glacial acetic acid and 63.3 parts of concentrated sulfuric acid is shaken with hydrogen at a pressure of 3 atmospheres until 2 molecular equivalents of hydrogen are absorbed. The reaction mixture is then filtered and the resulting filtrate is mixed with 100 parts of solid sodium acetate. Evaporation of the mixture to dryness affords a solid residue which is extracted with water. The resulting extract is filtered and the filter cake is washed with water, dried, then recrystallized from acetone to afford white crystals of 2,5-dioxocyclopentaneheptanoic acid, melting at about 160°-161.5°.

후처리

  1. customare absorbed
  2. filtrationThe reaction mixture is then filtered
  3. additionthe resulting filtrate is mixed with 100 parts of solid sodium acetate
  4. customEvaporation of the mixture to dryness
  5. customaffords a solid residue which
  6. extractionis extracted with water
  7. extractionThe resulting extract
  8. filtrationis filtered
  9. washthe filter cake is washed with water
  10. customdried
  11. customrecrystallized from acetone

출처 및 근거

ORD 기록
ord-ab2ddea3cbb34e2ba3cc8eb5f944938c
출처 데이터셋
uspto-grants-1976_01
특허 번호
US03931411

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